Instituto de Investigación Sanitaria Gregorio Marañón

Biomedical research at Gregorio Marañón

The Gregorio Marañón Health Research Institute (IiSGM) is a biomedical research center in Madrid affiliated with Gregorio Marañón General University Hospital. Its research spans biomedical engineering; cardiovascular disease; neuroscience and mental health; clinical microbiology and infectious diseases; immune-system disorders; translational oncology; major-organ diseases and transplantation; and nursing and health-care management innovation.

Research platforms and facilities

The institute’s technology platforms support several areas of research:

• Molecule Platform: bioinformatics, proteomics, genomics and cytogenetics, cytogenomics, and molecular biology.
• Cell Platform: pathology, confocal microscopy, cell cultures, flow cytometry and cell sorting, and a production unit for advanced therapy medicines.
• Animal Platform: preclinical molecular imaging, an animal facility, and an experimental operating room.
• Organ Platform: 3D printing, a translational cardiology research laboratory, and a biobank.
• Patient Platform: advanced neuroimaging processing, IT services, cardiac imaging, an innovation support unit, clinical trials and studies, and methodology and biostatistics.

Innovation and research support

The Innovation Support Unit (UAI) coordinates ideas and proposals from the hospital and is part of the ITEMAS Platform, funded by Spain’s Carlos III Health Institute. IiSGM also provides innovation support, a technology portfolio, and invention policies, and participates in funding calls such as AES 2026.

Training and education

The institute organizes its own courses, seminars, conferences, and external courses for health professionals and researchers.

Research activity at a glance

• 1,268 researchers.
• 147 active competitive projects.
• 1,965 active clinical studies and trials.
• Total impact factor: 6,962.
• 1,206 publications.
• 56% of publications in Q1 journals.

Address and transit

Calle Dr. Esquerdo 46, Government Pavilion Building, 28007 Madrid · Phone: +34 914 265 115. Nearby bus routes include 56, 143, 20, and 30 on Calle Dr. Esquerdo; 15 and 202 on Calle Ibiza; and 28 and 2 on Calle O’Donnell. Metro access is available on Line 6 at O’Donnell or Sainz de Baranda and Line 9 at Ibiza or Sainz de Baranda.